The Biology & Drug Discovery Experts
Based in Glasgow, UK, our modern laboratories and experienced Life Science professionals provide expertise in biology and drug discovery services tailor-made to suit your needs.
Our molecular biology and protein biochemistry teams clone and express Client-specified targets on demand for use in biochemical assays, in vivo studies or crystallography and offer a range of high quality human recombinant enzymes such as PDEs for sale. Together with our cell biologists, SB's molecular and protein experts form an interdisciplinary team capable of developing fully validated stable cell lines over-expressing your target of choice. Our expertise has enabled us to generate a range of ion channel cell lines including the complete ion channel panel for licence-free purchase.
As experts in cell signaling, SB specialises in cell-based and in vitro biochemical assays to determine compound effects on druggable targets including PDEs, ion channels, GPCRs and kinases. As well as performing routine assays, SB also develops custom assays designed to meet your specific drug discovery requirements.
To complete our drug discovery service portfolio, SB offers a wide range of disease-relevant secondary assays and in vivo models. Using primary human or animal cells, fresh human tissue or stem cells, SB can study functional effects of lead compounds in disease-relevant assays while our in vivo team can perform models of inflammation, pain, CNS disorders and diabetes.
On behalf of its Clients, SB has applied advanced HTS and design technologies to discover new drugs interacting with enzymes, GPCRs, ion channels and signaling pathways that have found use in the treatment of inflammatory, metabolic, CNS and infectious diseases, cancer and pain. SB has assisted its Clients in producing candidates with increased potency, selectivity and superior ADMET properties and is proud of the role it has played in the development of a number of NCEs presently in phase III trials and in market.
Trust SB's experienced professionals and let our multidisciplinary team advance your early stage drug discovery projects.
