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PDE screening & profiling

The flexible PDE screening service

Scottish Biomedical offers both the “Gold Standard” radiometric PDE assay and the indirect fluorescent assay for screening and profiling of PDE inhibitory compounds.  Each assay uses recombinant enzyme expressed in insect cells, providing active enzyme with mammalian-like modifications.

Our team will custom design plate plans to suit your needs. Whether you require a single IC50 value for your lead compound, selectivity profiling across a range of PDEs or HTS using a library of your choice, SB’s reliable PDE screening service guarantees data you can trust.

  • “Gold standard” radiometric or fluorescent assays
  • HTS, selectivity profiling or dose response curves
  • Flexible plate set-up options
  • Largest range of full length PDEs and catalytic domains
  • Zoological panel
  • Reference inhibitors included in all assays
  • Fast turnaround time

Trust the experts, Request a quote for PDE screening & profiling.