Protein Interaction

Scottish Biomedical's protein interaction service includes a range of assays to identify novel protein-protein interactions including Yeast-2-Hybrid, co-immunoprecipitation and SILAC (Stable Isotope labeling of Amino Acids).

We can further elucidate the residues critical for interaction using our Protein Partner Array Technology which rapidly and precisely reveals and maps sites critical to the interaction. As it also directly measures the affinity of molecules for key residues within the interaction site, Protein Partner Array can be seamlessly applied to screen libraries for compounds which specifically disrupt individual protein-protein interaction sites.

• Discover novel interacting proteins using SILAC technology
• Identify key interaction sites between proteins
• Rapid follow through into high throughput screen
• Cell-based assay to determine binding affinities & kinetics
• Produce quality leads combining high affinity with selectivity for the protein binding site

Contact us for further information on how SB can advance your protein interaction studies.